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Most studies employing specific FTIs, however, have been conducted on H-Ras systems, even though mutations in K-Ras are primarily associated with human cancer e. Autologous stem cell transplantation in autoimmune and rheumatic diseases: In their recent review, Cox and Der proffer the explanation that this disparity between ras mutation status and ability to be inhibited by FTI may be a function of whether a tumor is Ras-dependent rather than simply its ras mutation status All the time go after your heart.
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